AFFINISOL HPMC has been specifically designed for generating solid dispersions via spray-drying (SDD) or hot melt extrusion (HME) in the pharmaceutical industry. Their nomenclature and recommended applications are shown below: Co-processed Avicel grades are high functionality materials designed to bring added performance over and above what standard grades offer. : 160182 Date Approved: 05/25/2010 Revision No. Material safety data sheet (MSDS) of the m icrocrystalline cellu lose (MCC) CAS #: 9004-34-6 "R}~Q:~pgg'"l/O:OV~ @zo7g;)K;=d'}z8}7w7?Iuw?w~ikK^^'d4k;g_u_LOC6($uiz["Dw#j{ogw~0B"ty'{DqXmImPiww#({LDo^/w;?EW>;b$l/fmQ-1GG/jls}>N\UbZWi,`:O?e;hD8}uC?L{yiD>_2?0 :f =eU}|r=r?P5){{o:tzY- F kNdOaM;p0Nmm7A!Va/eWzgT5vw Ur?0J. XiDqLN MD'F2`jI7ZWu,JK%5e9~:R>LAm\WyY0lk=ZNP;pZ23)P0GG~%e[ d8GIXRo&. Find answers in our support articles. Some substance identifiers may have been claimed confidential, or may . To meet their exacting standards, we deliver a wide choice of relevant solutions that are simultaneously replicable, scalable and high performing. Trademarks: Avicel PH-102. EINECS #: 232-674-9 1.7. Microcrystalline cellulose 9004-34-6 <1 Synonyms are provided in Section 1. 9,LL!z endstream Avicel Microcrystalline Cellulose: Chemical Identifiers. Description: Microcrystalline Cellulose E460 is a term for refined wood pulp manufactured through plant fibre hydrolysis. Various Gelcarin and Viscarin carrageenan grades are used by the pharmaceutical industry to achieve specific gelling for controlled drug release, thickening, and stabilizing properties desired in various formulations. Hi, let us know if you have any questions as you visit our website. Avicel RC-591 offers ideal thixotropic bahavior for stabilizing suspensions while Avicel CL-611 is a stabilizer for reconstitutable or dry suspension formulations. They are differentiated from each other by the amount of 3,6-anhydrogalactose as well as the number and position of ester sulfate groups present. microcrystalline cellulose and carboxymethylcellulose sodium NF, Ph. Explore our end markets, products, ingredients and essential solutions or get in touch with us about your order. cas:9004-36-8 msds CELLULOSE ACETATE BUTYRATE. : 1. Created Date: 2/10/2020 8:51:41 PM . %PDF-1.4 FMC Corporation: Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations DE102009022738A1 (de) * 2009-05-26: 2010-12-09: J. Rettenmaier & Shne Gmbh + Co. Kg . Explore how we work and why we apply science and creativity for a better world to everything we do. Tel: 1-239-598-5088 sales@espllc.us www.espllc.us. All Rights Reserved. Pharmacel 112 can be used in a wide range of oral solid dosage (OSD) forms as binder, compressing agent . PDF PRODUCT OVERVIEW: Avicel RC-591 - Signet Truly distinctive drug delivery solutions. /Parent 3 0 R Place an order online, track your orders, download SDS and TDS, and see your quotes, all in one secure place. It is hygroscopic and insoluble in water. Material safety data sheet - FMC Corporation - YUMPU The UK Health & Safety Executive has set workplace exposure limits at 10 mg/m3 long-term (8 hr TWA) for total inhaled dust and 4 mg/m3 for respirable dust. Microcrystalline Cellulose (MCC) Manufacturing | Pharmaceutical Grade Safety Data Sheet for Cellulose microcrystalline 102331. Chemical Formula: (C6H10O5)n 1.4. Chemical Formula: (C6H10O5)n 1.4. Microcrystalline Cellulose (MCC) Manufacturing Industry. Avicel CL-611 Microcrystalline Cellulose and Sodium Carboxymethylcellulose Page 1 of 9. MATERIAL SAFETY DATA SHEET. <>/ExtGState<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 612 792] /Contents 6 0 R/Group<>/Tabs/S>> Watch Now. Test Data Available. ( <> Microcrystalline Cellulose. Battista, O. Ac-Di-Sol Croscarmellose Sodium is one of our flagship offerings for pharmaceutical manufacturers. ]c\RbKSTQ C''Q6.6QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ p@" IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Material Name: Estradiol Tablets Trade Name: RONFASE . 2021 Annual Report. Remove Avicel RC-591 & CL-611 | IMCD US G2W4de=u183KGH{ vQ#4:1\wc All Rights Reserved. CAS #: 9004-34-6 . gwf;J(e0o|1p{R~P^);ao!%{0KD7. < gV2@o2s&WS@Et%Up:`U '_ h?8qyP=&> GFprm9A!uu1 }&*kQ c^&eX}^K}h9YCb2L(yL):,+g8_u. Excipients for Pharmaceuticals | Products | IFF - DuPont F. Steele, M. Tobyn, S. Edge, A. Chen & J. N. Staniforth.Physicochemical and Mechanical Evaluation of a Novel High Density Grade of Silicified Microcrystalline Cellulose, Drug Development and Industrial Pharmacy, 30:1 (2004), 103-109. Molecular weight: Not Applicable 1.5. No: 9004-34-6-5 Version: Global Date Approved: 10/16/1998 . Catalog Number 102331. All rights reserved. TEXTURECEL is highly purified sodium carboxymethyl cellulose (NaCMC) that forms clear solutions in water at all temperatures, has exceptional water binding properties, and is available in a wide range of viscosity grades. Aquacoat ECD is an aqueous dispersion of ethylcellulose used for sustained release barrier or slow release pharmaceutical coating, moisture barrier and taste masking applications for tablet and multi-particulate dosage forms. PROSOLV SMCC, silicified microcrystalline cellulose, is a unique combination of microcrystalline cellulose (MCC) and colloidal silicon dioxide (CSD).A high functionality and multifunctional excipient, it requires less complex processing, has high inherent functionality, and passes that functionality on to the drug formulation. 1.3. 8 0 obj MATERIAL SAFETY DATA SHEET Lattice NT Microcrystalline Cellulose MSDS Ref. Heavy metals, % NMT 0.001 Meet our leadership team. LATTICE Microcrystalline Cellulose has many important uses within the food, pharma, specialty applications and industrial such as non-stick coatings, insulation of wiring, crop protection and paints,coats and inks. The typical mean particle size is 20200 m. Product Name: Microcrystalline Cellulose E460 1.2. HAZARDS IDENTIFICATION EMERGENCY TELEPHONE NUMBERS (302) 451-0100 (FMC Plant - Newark, Delaware) (303) 595-9048 (Medical - U.S. - Call Collect) For leak, fire, spill, or accident emergencies, call: (800) 424-9300 (CHEMTREC - U.S.A. & Canada) (703) 527-3887 (CHEMTREC - Collect - All Other Countries) EMERGENCY OVERVIEW: Off-white, free-flowing, odorless powder. In extrusion-spheronisation, it is the excipient of choice. PDF Microcrystalline Cellulose MSDS manufacturers Microcrystalline Cellulose / Avicel PH-102. ?t#_n|z%4n#(!:lMD~{mfvv}Na0vx?? It is, however, a good source of fibre. Burger King, McDonald's and other fast food companies list in the ingredients of several of their foods, microcrystalline cellulose (MCC . Regulatory Information This paper is based on a study of the interactions that take place during the process of hydrogel formation, break down, and recovery. Comments: The human studies including the use of radiolabelled microcrystalline cellulose show complete absence of digestion or absorption. Packaging: 34 x 50 kgs fiber drums. Manufactured by: China . l~5C Medium size standard MCC grade, suited for the majority of directly compressible actives. (PDF) Commercial sources of "Avicel RC/CL" and its - ResearchGate Cellulose microcrystalline CAS 9004-34-6 | 102331 - EMD Millipore The global microcrystalline cellulose (MCC) market was valued at $401.1 million in 2021, and is projected to reach $712.9 million by 2031, growing at a CAGR of 5.9% from 2022 to 2031. Aquacoat CPD is an aqueous dispersion of cellulose acetate phthalate used for enteric release applications. Microcrystalline Cellulose Side Effects. Production of Pharmaceutical Grade Microcrystalline Cellulose. Avicel Microcrystalline cellulose is a type of cellulose, a naturally-occurring, large molecular weight polysaccharide found in woody plants. Product Name Cellulose microcrystalline. The table below lists the typical nutritional information of microcrystalline cellulose: Quantitative nutritional analysis of Avicel Microcrystalline cellulose (in 100g)1. stream It is a white, free-flowing powder. It is also inert and biocompatible. : CL-611NF Date Approved: 01/13/2010. Avicel PC 611 (FMC Biopolymer) Supplied by. 10.1 Future Forecast of the Global Microcrystalline Cellulose Market from 2023-2028 Segment by Region 10.2 Global Microcrystalline Cellulose Production and Growth Rate Forecast by Type (2023-2028 . Interestingly, the discovery of Avicel was accidental, the team was attempting to break up hydrolysed cellulose . [FMC Study Number I92-1464]. List of Microcrystalline Cellulose Products and Manufacturers Microcrystalline cellulose is a term for refined wood pulp and is used as a texturizer, an anti-caking agent, a fat substitute, an emulsifier, an extender, and a bulking agent in food production. Upon ingestion, microcrystalline cellulose is not absorbed into the blood stream and therefore has little toxicological potential. /Type/Page MATERIAL SAFETY DATA SHEET - Sevron Learn about FMC's industry leading goal of net-zero emissions by 2035. }o]X4]. As one of the most robust and efficient excipients, it tolerates high salt content, high temperature and is stable in a wide pH range. SEM micrographs of microcrystalline cellulose (MCC) models with a scale bar of 100 m [1] . Assay: 0.98 Appearance: Off white to slight yellow solid Package: 1L 5L 10L 25L bottle Storage: Stored in shaded, cool and dry places Transportation: Handle with cares to avoid damaging the packages. Alginates from IFF are an excellent choice for consistent performance in a variety of applications. Fmc Corporation: Ultra-fine microcrystalline cellulose compositions and process . An internally cross-linked sodium carboxymethyl cellulose (NaCMC), it aids in the disintegration and drug dissolution of pharmaceutical tablets, capsules, and granules. Well-recognized product that can do it all. on Avicel microcrystalline cellulose, the most trusted excipient brand for decades. GRINDSTED Xanthan Gum is a naturally fermented product of carbohydrates and is applied in various liquid, semi-solid and solid pharmaceutical dosage forms. No. Microcrystalline Cellulose Market Share, Trend, Statistics - 2031 To help, weve put together a simple guide for selecting Avicel Microcrystalline cellulose grades, with simple explanations of some of the most common grades, plus recommendations that will serve the majority of buyers. Microcrystalline Cellulose, Colloidal Silicon Dioxide: 50: 0.20 - 0.30: Best in class binder. FMC Corporation. Microcrystalline cellulose 9004-34-6 232-674-9 Not Listed * Magnesium stearate 557-04- 209-150-3 Not Listed * MATERIAL SAFETY DATA SHEET Avicel PC 611 Microcrystalline Cellulose Page 1 of 8 MSDS Ref. CeolusTM UF-702, MSDS No.060EU MATERIAL SAFETY DATA SHEET NTP: Not listed ACGIH: Not listed 12. Microcrystalline cellulose (C6H10O5)n is refined wood pulp. : 9 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication . The wood pulp is depolymerized by acid hydrolysis and turned from a fibrous material to a white freely-flowing powder. TEXTURECEL NaCMC is applied in oral solids, such as granules and pellets, powders as well as coatings for tablets. : 5. Its used in capsules and tablets, both in wet granulation and direct compression processes, where it serves as a moisture adsorbent, tablet, and capsule diluent, and tablet disintegrant.It is also widely used as a supplementary formulation aid, primarily to enhance the . Global Wood Pulp Based Microcrystalline Cellulose Market - Industry Reports CAS 9004-34-6, pH 5 - 7.5. Slightly soluble in 5% w/v sodium hydroxide solution; practically insoluble in water, dilute acids, and most organic solvents. 3 0 obj gac74 [#B6`Wnw7 Product and Company Identification Product Name Microcrystalline Cellulose CAS Number 9004-34-6 Parchem - fine & specialty chemicals 415 Huguenot Street New Rochelle, NY 10801 (914) 654-6800 (914) 654-6899 parchem.com info@parchem.com EMERGENCY RESPONSE NUMBER The highly reactive amorphous regions selectively hydrolyze, releasing the crystallites, which are subsequently mechanically dispersed. pb7c8BHqCRX_eL +90w~ gk[YBkf9eDNJdNn q^16mi=4Sr0~{lZ>yvMqS'e,MqB?;Oy9s'$8asJgEh0SS>|J58ub^q c Dh)#t'kTfIZT1-_y"+wXj,qo!~ozc}ZemZ``$'vj{, Ga;]2iY*DIh~F3Z!.pkL:bHHBTbIcw9.Xo$4,?On4s=R,KLz /M|#PF(j%j oF2[5 ,rx)bd1$LM4Dc-d\@W D?A?L/7>s]-};Z if^+e3}AeQ# U%l3K?WW$iJ:tSS8M /&N2R3d2Nl2u]qg*WVkq2lhJZIiE++nKfq)sO~z(d| 7u4w!o}::#l}tEw'M}BEntaugq**t|KZUTe-1J+|. It can be processed both via wet granulation and direct compression, as well as roller compression and extrusion-spheronisation. Microcrystalline Cellulose (Inactive Ingredient) - Drugs.com Microcrystalline Cellulose (Mcc) Market Research Report 2023-2026 Microcrystalline Cellulose NF. Microcrystalline cellulose has excellent compressibility properties and is widely used in solid forms such as tablets that are hard, but can dissolve quickly, and this has increased its demand in . In many applications, one METHOCEL product can perform the job of two, three or even more ingredients saving money and time. stream Quantity: 1 700 kgs. Description:Chemical PropertiesMicrocrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. : 5 This document has been prepared to meet the requirements of the U.S. OSHA Hazard Communication Standard, 29 CFR 1910.1200 and Canadas Workplace Hazardous Materials Information System (WHMIS) requirements. q9;v80 1 0 obj Cellulose microcrystalline MSDS - 102331 - Merck Since cellulose contains both amorphous and crystalline regions, when the crystalline regions are mechanically and chemically isolated and elaborated, various useful ingredients in the form of cellulose crystals are obtained, one of which is Avicel Microcrystalline cellulose. Product and Company Identification . It is insoluble in water, dilute acids, common organic solvents and oils, partially soluble with . ETHOCEL premium ethylcellulose resins are water-insoluble polymers. PDF MATERIAL SAFETY DATA SHEET - Stobec Alubra sodium stearyl fumarate from IFF Pharma Solutions is a comparatively hydrophilic lubricant widely used in capsule and tablet formulations. JFIF ` ` ZExif MM * J Q Q Q C Revision No. Gloves, eye protection and a dust mask should be used. 2 0 obj Avicel Microcrystalline cellulose was discovered in 1955 by a team at FMC Corporation, led by the legendary Canadian-born chemist, Orlando Aloysius Battista, which he initially named 'mechanically disintegrated D.P cellulose.
Western Show Shirt Appliques,
Spreader Bar Lifting Device Calculations And Design Excel,
Old West Execution Photos,
Lincoln City Accident Today,
Celebrities With Libra Venus,
Articles M